Applicants are invited to submit a brief summary of their proposed project to reach Climb on or before the 30th October each year. The summary is to include outline costings and timeframe. This outline will be used only to establish whether the project falls within Climb’s criteria. Where the proposed project falls within Climb’s remit for funding research, the applicant will be asked to complete a full, detailed application form. There is one deadline for receipt of the full application form each year which is 21st December.

On receipt of the completed application form, the project will be peer-reviewed. The peer-review reports will be submitted to a meeting of the multi-disciplinary Climb Research Sub-Committee who will make recommendations based on these reports to the Board of Directors/Trustees. Sub-Committee meetings take place in March each year with their recommendations being put to a full Board meeting in April or early May. Applicants will be notified of the outcome of their application by the end of May.

Late applications will be withdrawn if ‘out of time’ for the applicant.

Grant payments will only be made in the financial year for which they are applicable and will be paid by monthly BACS transfer over a 6 month period, normally starting in July.

Following an agreement to fund a project, either in full or in part, the applicant will be asked to agree to and sign the ‘Conditions of Grant Support’, funding will not be released until the completed Conditions document is received. As part of the Conditions of Grant Support, the applicant will agree to provide regular reports (as detailed in the conditions) on the progress of the project and the balance of the grant may be withheld until a satisfactory interim report has been received. Assessment of the reports will be via the same peer review process as the original application. A report on completion of the project is also a condition of grant support. Climb will retain all rights to the research (including intellectual/intellectual property rights) and expects appropriate acknowledgement of its support in any publication, trade fair or presentations of any type.

For example; you forward your brief summary which reaches Climb in October, this is then internally assessed for relevance and a full application requested. If the full application is received by the end of December, this is then forwarded for peer review. The peer reviews are received in Climb by the end of February and submitted to the Research Sub-Committee in March. The recommendations of the Sub-Committee are then submitted by the Executive Director to the full Board at the next available meeting (which is normally in April or May). The applicant would be informed of the outcome of their application by the end of May at which time the project if successful, could commence, subject to Climb receiving the appropriate signed Conditions of Grant Support.

Climb will only fund research into metabolic diseases. In addition, any restricted funds will also be directed, according to the restrictions placed on them by donors, towards type specific research. Climb may pump-prime an important, innovative project or fund one more fully. Grants are likely to be up to a maximum of £15,000 and Climb is unlikely to fund salaries at a senior level.

European applicants of any award requiring the use of In Vitro Medical Devices should ensure that they have registered their research with, and taken advice from, the Medical Devices Agency to comply with the In Vitro Diagnostic Directive (IVDD). No project will be considered for funding if ethical approval is required but not obtained.

Please submit your outline project, which must include timeframe and outline budgets to Climb.

We are particularly interested in funding research for 2009/2010 in:

Amino Acid/Urea Cycle Disorders and

Hormone Disorders

Congenital Adrenal Hyperplasia

The above research areas will only be considered if they are in relation to Inherited Metabolic Diseases

Deadline for applications

Outline Summary (inc budget) 30th October 2008

Full Application 19th December 2008